98977-36-7
- Product Name：1-Boc-3-piperidone
- Molecular Formula：C10H17NO3
- Purity：99%
- Molecular Weight：199.25
Product Details;
CasNo： 98977-36-7
Molecular Formula： C10H17NO3
Appearance： white to yellow low melting solid
Factory Sells 1-Boc-3-piperidone 98977-36-7 Factory Supply with Lowest Price
- Molecular Formula:C10H17NO3
- Molecular Weight:199.25
- Appearance/Colour:white to yellow low melting solid
- Vapor Pressure:0.002mmHg at 25°C
- Melting Point:35-40 °C(lit.)
- Refractive Index:1.481
- Boiling Point:289.825 °C at 760 mmHg
- PKA:-1.71±0.20(Predicted)
- Flash Point:129.082 °C
- PSA：46.61000
- Density:1.099 g/cm3
- LogP:1.52430
1-Boc-3-piperidone(Cas 98977-36-7) Usage
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Chemical Properties |
White to yellow low melting solid |
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Uses |
1-Boc-3-piperidone, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. |
InChI:InChI=1/C10H17NO3/c1-10(2,3)14-9(13)11-6-4-5-8(12)7-11/h4-7H2,1-3H3
98977-36-7 Relevant articles
Industrial adaptability selection for a novel ω-transaminase
Wang J 1 , Xie Y 1 , Wang H 1 , Wei D 1
, Chinese Journal of Biotechnology, 01 Sep 2020, 36(9):1929-1938
The strain could convert 20 mmol/L 1-Boc-3-pyrrolidinone and 20 mmol/L 1-Boc-3-piperidone with 85.84% and 67.42% conversion rate, respectively, in a 1-mL scale with isopropylamine (IPA) as amine donor.
Preparation method of N-tert-butyloxycarbonyl-3-piperidone and derivative thereof
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Paragraph 0061-0065; 0067-0068; 0071, (2020/07/21)
The invention discloses a preparation me...
A pharmaceutical intermediate N - BOC - 3 - piperidone preparation method (by machine translation)
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Paragraph 0055; 0059-0061; 0076-0077, (2018/03/01)
The invention belongs to the field of or...
An investigation into the role of 2,6-lutidine as an additive for the RuCl3-NaIO4 mediated oxidative cleavage of olefins to ketones
Watson, David W.,Gill, Matthew,Kemmitt, Paul,Lamont, Scott G.,Popescu, Mihai V.,Simpson, Iain
supporting information, p. 4479 - 4482 (2018/11/23)
2,6-Lutidine has been identified as a be...
98977-36-7 Process route
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- 85275-45-2
N-tert-butoxycarbonyl-3-piperidinol
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- 98977-36-7
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
| Conditions | Yield |
|---|---|
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With sodium hypochlorite solution; sodium hydrogencarbonate; potassium bromide; In dichloromethane; at 5 - 10 ℃; pH=8.5; Reagent/catalyst;
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99.4% |
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With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide; In dichloromethane; at 0 - 10 ℃; for 1h;
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98.3% |
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With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 22h; Inert atmosphere;
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97% |
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With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; sodium bromide; In diethyl ether; water; toluene; at 0 - 4 ℃;
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95% |
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With Dess-Martin periodane; In dichloromethane; at 0 - 20 ℃; for 18h;
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86% |
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With 4-methylmorpholine N-oxide; tetrapropylammonium perruthennate; In dichloromethane; at 0 - 20 ℃; for 1.33333h;
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75% |
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With pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 3.25h;
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19% |
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With pyridine; chromium(III) oxide; acetic anhydride; In dichloromethane; Yield given;
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With pyridine-SO3 complex; triethylamine; In dichloromethane;
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With N-methyl-2-indolinone; tetrapropylammonium perruthennate; 3 A molecular sieve; In dichloromethane; for 1h;
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With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -70 ℃;
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With N-methyl-2-indolinone; tetrapropylammonium perruthennate; 4 A molecular sieve; In dichloromethane; acetonitrile; for 1h;
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With trimethyl-sulfo-ammonium betaine; dimethyl sulfoxide; triethylamine; at 20 ℃; for 18h;
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15.6 g |
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With trioxide-trimethylamine; triethylamine; In dimethyl sulfoxide; at 20 ℃; for 18h;
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15.6 g |
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With trimethyl-sulfo-ammonium betaine; dimethyl sulfoxide; triethylamine; at 20 ℃; for 18h;
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Multi-step reaction with 2 steps
1: (COCl)2 / CH2Cl2 / 1 h / -70 °C
2: Et3N / CH2Cl2 / 1 h / 0 °C
With oxalyl dichloride; triethylamine; In dichloromethane; 1: Swern oxidation / 2: Swern oxidation;
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With triethylamine; In dimethyl sulfoxide; for 2h;
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With pyridinium chlorochromate; In dichloromethane;
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With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; In dichloromethane; at 20 ℃;
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With oxalyl dichloride; dimethyl sulfoxide; triethylamine; at 20 ℃; for 10h;
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With sulfur trioxide trimethylamine complex; triethylamine; In dimethyl sulfoxide; at 20 ℃; for 18h;
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With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium; sode de l'acide trichloroisocyanurique; sodium bromide; In dichloromethane; water; at 5 ℃; for 4h; Reagent/catalyst; Time; Temperature;
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-
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1-benzyl-piperidin-3-one hydrochloride hydrate
-
- 98977-36-7
3-oxo-piperidine-1-carboxylic acid tert-butyl ester
| Conditions | Yield |
|---|---|
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With hydrogen; palladium dihydroxide; In methanol; dichloromethane;
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97% |
98977-36-7 Upstream products
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24424-99-5
di-tert-butyl dicarbonate
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50717-82-3
piperidin-3-one
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85275-45-2
N-tert-butoxycarbonyl-3-piperidinol
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6859-99-0
3-hydroxypiperazine
98977-36-7 Downstream products
-
98977-39-0
tert-butyl 1,3,5,6,7,8-hexahydro-3-oxo-4H-isoxazolo<4,3-c>azepine-5-carboxylate
-
98977-40-3
tert-butyl 1,3,5,6,7,8-hexahydro-3-oxo-4H-isoxazolo<4,3-c>azepine-7-carboxylate
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98977-41-4
1-(tert-butyloxycarbonyl)-3-oxoperhydroazepine-4-hydroxamic acid
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98977-37-8
ethyl (+/-)-1-(tert-butyloxycarbonyl)-4-oxoperhydroazepine-3-carboxylate
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