14813-01-5

  • Product Name:1-Benzyl-3-piperidinol
  • Molecular Formula:C12H17NO
  • Purity:99%
  • Molecular Weight:191.273
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Product Details;

CasNo: 14813-01-5

Molecular Formula: C12H17NO

Appearance: White solid

Buy Reliable Quality High Purity 1-Benzyl-3-piperidinol 14813-01-5 Fast Delivery

  • Molecular Formula:C12H17NO
  • Molecular Weight:191.273
  • Appearance/Colour:White solid 
  • Vapor Pressure:0.000631mmHg at 25°C 
  • Melting Point:168-172oC 
  • Refractive Index:n20/D 1.549  
  • Boiling Point:296.8 °C at 760 mmHg 
  • PKA:14.82±0.20(Predicted) 
  • Flash Point:96.3 °C 
  • PSA:23.47000 
  • Density:1.106 g/cm3 
  • LogP:1.58120 

1-Benzyl-3-piperidinol(Cas 14813-01-5) Usage

Chemical Properties

Colorless liquid

Uses

1-Benzyl-3-piperidinol is a piperidine derivative. Reactant for bioresolution of tertiary amino ester protic ionic liquids using subtilisinReactant for synthesis of:Muscarinic M3 selective antagonistsRho kinase inhibitorsPiperidine derivatives for investigations into α-adrenoreceptor direct activation

InChI:InChI=1/C12H17NO/c14-12-7-4-8-13(10-12)9-11-5-2-1-3-6-11/h1-3,5-6,12,14H,4,7-10H2

14813-01-5 Relevant articles

N-alkylpiperidine carbamates as potential anti-Alzheimer's agents

Brazzolotto, Xavier,Gobec, Stanislav,Knez, Damijan,Kos, Janko,Nachon, Florian,?akelj, Simon,Juki?, Marko,Ko?ak, Urban,Pi?lar, Anja,Stra?ek, Nika,Zahirovi?, Abida

, (2020)

Compounds capable of interacting with si...

Transition-Metal-Free Total Synthesis and Revision of the Absolute Configuration of Pipermethystine

Quintero, Leticia,Rodr?guez-Molina, Braulio,Sartillo-Piscil, Fernando,Vázquez-Amaya, Laura Y.

, p. 3949 - 3953 (2020)

Starting from 3-hydroxy piperidines, a n...

Haemoprotein-mediated metabolism of enamines and the possible involvement of one-electron oxidations

L. M. Sayre,D. A. Engelhart,D. V. Nadkarni,M. K. M. Babu,M. E. Klein &G. McCoy

, Xenobiotica the fate of foreign compounds in biological systems Volume 25, 1995 - Issue 7

The selective prevention by cyanide of the metabolite production of 1-benzyl-3-piperidone but not 1-benzyl-3-piperidinol from 1-BP is consistent with the enamine as the source of the 3-one metabolite.

14813-01-5 Process route

piperidin-3-ol hydrochloride
64051-79-2,198976-43-1

piperidin-3-ol hydrochloride

benzyl chloride
100-44-7

benzyl chloride

1-benzyl-3-hydroxypiperidine
14813-01-5

1-benzyl-3-hydroxypiperidine

Conditions
Conditions Yield
With triethylamine; In toluene;
56.9%
1-benzyl-3-piperidone
40114-49-6

1-benzyl-3-piperidone

1-benzyl-3-hydroxypiperidine
14813-01-5

1-benzyl-3-hydroxypiperidine

Conditions
Conditions Yield
1-benzyl-3-piperidone; With sodium tetrahydroborate; In ethanol; at 20 ℃;
With hydrogenchloride; In water;
86%
With sodium tetrahydroborate;
 

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